Clinical Evidence & Background

Built on Science. Validated in Practice.

MGrx is the result of years of clinical research into meibomian gland dysfunction — the leading cause of dry eye disease. Every design decision is backed by peer-reviewed evidence and real-world provider feedback.

Our Mission

We exist to close the gap between what dry eye patients need and what current treatment options deliver. MGrx was developed to give eye care providers a fast, effective, and evidence-based tool that fits the realities of a busy practice — without sacrificing clinical outcomes.

The Clinical Case for MGrx

51%
improvement in OSDI after one single session
12 min
average in-office treatment time with zero patient downtime
30,000+
dry eye patients successfully treated
90%
of clinican's purchase the MGrx after the 2-week trial period

Clinically Proven Effective in One Treatment

Four peer-reviewed studies confirm that a single MGrx session produces statistically significant, measurable improvements in dry eye symptoms and objective clinical markers.
Open Ophthalmology Journal· 2023· McMurren et al.
51% OSDI improvement

Triple Therapy for Meibomian Gland Dysfunction: Microdermoabrasion, Heat, and Meibomian Gland Expression

A single MGrx treatment session produced statistically significant improvements in OSDI symptom scores and NIKBUT tear film stability. Patients demonstrated measurable relief from evaporative dry eye disease after one in-office visit.

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Pan American Journal of Ophthalmology· 2024· Valdez-Garcia et al.
100% gland improvement

Meibomian Gland Dysfunction Treated with a Novel Device: A Case Series

A case series evaluating MGrx in patients with MGD demonstrated consistent improvements in meibomian gland function and patient-reported dry eye symptoms following a single treatment session.

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Optometry and Vision Science· 2024· Semp & Wolffsohn
44% NIKBUT increase

Clinical Outcomes of Combined Thermal and Mechanical Therapy for Evaporative Dry Eye

Objective measures of tear film stability and meibomian gland expressibility showed statistically significant improvement following a single MGrx treatment, with patient-reported outcomes confirming sustained symptom relief.

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ARVO Annual Meeting· 2025· Ortiz, Valdez-Garcia et al.
37% OSDI reduction

Triple Therapy for Meibomian Gland Dysfunction with a Single Device: A Pilot Study

31 patients showed a 37% decrease in OSDI score, 44% increase in aNIKBUT, and 24% increase in iNIKBUT after a single MGrx session. All results were statistically significant (p ≤ 0.002), confirming rapid, objective improvement in tear film stability.

Read the Full Study

The Technology

Precision engineering meets clinical need.

Tri-Modal Treatment

MGrx delivers three therapeutic actions in a single session: Thermal Exfoliation gently removes debris and biofilm from the lid margin; Massage softens and mobilizes inspissated meibum within the glands; and Expression clears obstructed glands to restore healthy lipid secretion — all in one atraumatic pass.

Painless Atraumatic Expression

Simultaneous application of controlled heat and gentle mechanical expression addresses both the thermal and physical components of meibomian gland obstruction — the same mechanism validated in peer-reviewed literature.

Built-In Dry Eye Diagnostic

The MGrx features an integrated touchscreen patient survey that administers validated dry eye questionnaires — including OSDI — directly on the device before and after treatment. Results are captured automatically, giving clinicians objective before-and-after data at the point of care without additional software or manual entry.

FDA Registered & Clinically Validated

MGrx is FDA registered and has undergone rigorous clinical validation. Our device meets the safety and efficacy standards required for use in licensed eye care practices across the United States.

Clinical Advisory Team

MGrx was developed in close collaboration with leading optometrists and ophthalmologists specializing in ocular surface disease.

Dr. Rebecca Holloway

OD, FAAO, Dipl. ABO

Chief Clinical Advisor

Dr. Holloway brings over 18 years of specialty dry eye practice experience. She has published extensively on meibomian gland dysfunction and serves on the editorial board of the Ocular Surface journal.

Dr. Marcus Chen

MD, PhD

Research Director

Dr. Chen leads MGrx's clinical research program. His laboratory work on lipid layer dynamics and thermal therapy mechanisms formed the scientific foundation for the device's treatment protocol.

Dr. Anita Patel

OD, FSLS, FAAO

Clinical Education Lead

Dr. Patel oversees provider training and clinical onboarding. She has trained over 300 eye care professionals in advanced dry eye management and specialty contact lens fitting.

Ready to See the Evidence in Your Practice?

Start a 2-week trial and measure the outcomes yourself.